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Biodegradable polymethacrylic acid grafted psyllium for controlled drug delivery systems
Ranvijay KUMAR, Kaushlendra SHARMA
《化学科学与工程前沿(英文)》 2013年 第7卷 第1期 页码 116-122 doi: 10.1007/s11705-013-1310-0
关键词: psyllium acetyl salicylic acid in-vitro drug release swelling biodegradation
Acetyl salicylic acid attenuates cardiac hypertrophy through Wnt signaling
null
《医学前沿(英文)》 2015年 第9卷 第4期 页码 444-456 doi: 10.1007/s11684-015-0421-z
Ventricular hypertrophy is a powerful and independent predictor of cardiovascular morbid events. The vascular properties of low-dose acetyl salicylic acid (aspirin) provide cardiovascular benefits through the irreversible inhibition of platelet cyclooxygenase 1; however, the possible anti-hypertrophic properties and potential mechanism of aspirin have not been investigated in detail. In this study, healthy wild-type male mice were randomly divided into three groups and subjected to transverse aortic constriction (TAC) or sham operation. The TAC-operated mice were treated with the human equivalent of low-dose aspirin (10 mg·kg−1·d−1); the remaining mice received an equal amount of phosphate buffered saline with 0.65% ethanol, which was used as a vehicle. A cardiomyocyte hypertrophy model induced by angiotensin II (10 nmol·L−1) was treated with the human equivalent of low (10 or 100 µmol·L−1) and high (1000 µmol·L−1) aspirin concentrations in plasma. Changes in the cardiac structure and function were assessed through echocardiography and transmission electron microscopy. Gene expression was determined through RT-PCR and western blot analysis. Results indicated that aspirin treatment abrogated the increased thickness of the left ventricular anterior and posterior walls, the swelling of mitochondria, and the increased surface area in in vivo and in vitro hypertrophy models. Aspirin also normalized the upregulated hypertrophic biomarkers, β-myosin heavy chain (β-MHC), atrial natriuretic peptide (ANP), and b-type natriuretic peptide (BNP). Aspirin efficiently reversed the upregulation of β-catenin and P-Akt expression and the TAC- or ANG II-induced downregulation of GSK-3β. Therefore, low-dose aspirin possesses significant anti-hypertrophic properties at clinically relevant concentrations for anti-thrombotic therapy. The downregulation of β-catenin and Akt may be the underlying signaling mechanism of the effects of aspirin.
Xiaoxia OU, Chong WANG, Fengjie ZHANG, Yan MA, He LIU, Xie QUAN,
《环境科学与工程前沿(英文)》 2010年 第4卷 第2期 页码 157-163 doi: 10.1007/s11783-010-0018-3
Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar
G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA
《化学科学与工程前沿(英文)》 2014年 第8卷 第4期 页码 465-470 doi: 10.1007/s11705-014-1452-8
关键词: agar controlled drug release 5-Amino salicylic acid poly(2-hydroxyethylmethacrylate) grafted agar
LIU Fuqiang, CHEN Jinlong, LI Aimin, XIA Mingfang, FEI Zhenghao
《环境科学与工程前沿(英文)》 2007年 第1卷 第1期 页码 73-78 doi: 10.1007/s11783-007-0014-4
关键词: 5-sulfosalicylic bottle-point hypercrosslinked polymeric satisfactory separation NDA-100
Hossein Abdolmohammad-Zadeh, Arezu Salimi
《化学科学与工程前沿(英文)》 2021年 第15卷 第2期 页码 450-459 doi: 10.1007/s11705-020-1930-0
关键词: cadmium magnetic solid-phase extraction Fe3O4 nanoparticles Fe3O4/salicylic acid nanocomposite flame atomic absorption spectrometry
《化学科学与工程前沿(英文)》 2022年 第16卷 第8期 页码 1198-1210 doi: 10.1007/s11705-021-2133-z
关键词: solid acid catalyst mesoporous silica sulfonic acid biodiesel esterification oleic acid
《能源前沿(英文)》 2022年 第16卷 第5期 页码 697-699 doi: 10.1007/s11708-022-0843-7
《化学科学与工程前沿(英文)》 2023年 第17卷 第6期 页码 784-794 doi: 10.1007/s11705-022-2278-4
关键词: bismuth-ellagic acid in situ encapsulation enzyme@MOF biocomposites
Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 2101-2113 doi: 10.1007/s11705-023-2361-5
关键词: ursolic acid antibacterial activities reactive oxygen species apoptosis
Synergistic scale inhibition of polyaspartic acid composite with magnetic field
LIU Zhenfa, WANG Yanji, GAO Yuhua, ZHANG Lihui
《化学科学与工程前沿(英文)》 2007年 第1卷 第3期 页码 261-265 doi: 10.1007/s11705-007-0047-z
关键词: synergism magnetic PBTCA dynamic acid–acrylic acid–acrylic
Abiotic association of phthalic acid esters with humic acid of a sludge landfill
Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO
《环境科学与工程前沿(英文)》 2012年 第6卷 第6期 页码 778-783 doi: 10.1007/s11783-012-0434-7
关键词: abiotic association phthalic acid esters (PAEs) humic acid sludge landfill
New perspectives in free nitrous acid (FNA) uses for sustainable wastewater management
《环境科学与工程前沿(英文)》 2023年 第18卷 第2期 doi: 10.1007/s11783-024-1786-5
● The historical development of free nitrous acid (FNA) technologies is reviewed.
关键词: Free nitrous acid Acid-tolerant ammonia oxidizer In situ generation Wastewater management
Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric
《化学科学与工程前沿(英文)》 2022年 第16卷 第12期 页码 1751-1760 doi: 10.1007/s11705-022-2211-x
关键词: ARTP mutagenesis Bacillus licheniformis poly-γ-glutamic acid metabolomics
Proline-2′-deoxymugineic acid, a phytosiderophore analog, drives beneficial rhizobacterial community
《农业科学与工程前沿(英文)》 doi: 10.15302/J-FASE-2023531
● Proline-2′-deoxymugineic (PDMA) significantly altered the bacterial community in the peanut rhizosphere.
关键词: Beneficial rhizobacteria recruitment peanut plant-soil micronutrition enhancement proline-2′-deoxymugineic acid stable microbial network
标题 作者 时间 类型 操作
Biodegradable polymethacrylic acid grafted psyllium for controlled drug delivery systems
Ranvijay KUMAR, Kaushlendra SHARMA
期刊论文
Complexation of iron by salicylic acid and its effect on atrazine photodegradation in aqueous solution
Xiaoxia OU, Chong WANG, Fengjie ZHANG, Yan MA, He LIU, Xie QUAN,
期刊论文
Controlled drug release of 5-amino salicylic acid by poly(2-hydroxyethylmethacrylate) grafted agar
G. Usha RANI,Kartick Prasad DEY,Srijita BHARTI,Sumit MISHRA
期刊论文
Adsorption selectivity of salicylic acid and 5-sulfosalicylic acid onto hypercrosslinked polymeric adsorbents
LIU Fuqiang, CHEN Jinlong, LI Aimin, XIA Mingfang, FEI Zhenghao
期刊论文
A magnetic adsorbent based on salicylic acid-immobilized magnetite nano-particles for pre-concentration
Hossein Abdolmohammad-Zadeh, Arezu Salimi
期刊论文
Sulfonic acid-functionalized mesoporous silica catalyst with different morphology for biodiesel production
期刊论文
Amino acid promoted hydrogen battery system using Mn-pincer complex for reversible CO hydrogenation toformic acid
期刊论文
Enzyme@bismuth-ellagic acid: a versatile platform for enzyme immobilization with enhanced acid-base stability
期刊论文
Discovery of novel ursolic acid derivatives as effective antimicrobial agents through a ROS-mediated
期刊论文
Synergistic scale inhibition of polyaspartic acid composite with magnetic field
LIU Zhenfa, WANG Yanji, GAO Yuhua, ZHANG Lihui
期刊论文
Abiotic association of phthalic acid esters with humic acid of a sludge landfill
Xiaoli CHAI, Yongxia HAO, Xin ZHAO, Guixiang LIU, Ying ZHU, Rong JI, Jun WU, Huanhuan TONG, Youcai ZHAO
期刊论文
Genomic and metabolomic analysis of with enhanced poly--glutamic acid production through atmospheric
期刊论文